Toward Realistic Dosimetry <i>In Vitro</i>: Determining Effective Concentrations of Test Substances in Cell Culture and Their Prediction by an <i>In Silico</i> Mass Balance Model.

Dimitrijevic, Dunja; Fabian, Eric; Nicol, Beate; Funk-Weyer, Dorothee; Landsiedel, Robert

Toward Realistic Dosimetry In Vitro: Determining Effective Concentrations of Test Substances in Cell Culture and Their Prediction by an In Silico Mass Balance Model.

Dimitrijevic, Dunja; Fabian, Eric; Nicol, Beate; Funk-Weyer, Dorothee; Landsiedel, Robert.

Afiliación

Dimitrijevic D; Free University of Berlin, Institute of Pharmacy, Pharmacology and Toxicology, Königin-Luise-Straße 2-4, 14195Berlin, Germany.
Fabian E; BASF SE, Experimental Toxicology and Ecology, Carl-Bosch-Straße 38, 67056Ludwigshafen am Rhein, Germany.
Nicol B; Safety & Environmental Assurance Centre, Unilever U.K., Sharnbrook, MK44 ILQBedford, United Kingdom.
Funk-Weyer D; BASF SE, Experimental Toxicology and Ecology, Carl-Bosch-Straße 38, 67056Ludwigshafen am Rhein, Germany.
Landsiedel R; Free University of Berlin, Institute of Pharmacy, Pharmacology and Toxicology, Königin-Luise-Straße 2-4, 14195Berlin, Germany.

Chem Res Toxicol ; 35(11): 1962-1973, 2022 11 21.

Article en En | MEDLINE | ID: mdl-36264934

Asunto(s)

Acetaminofén; Técnicas de Cultivo de Célula; Ratones; Animales; Interacciones Hidrofóbicas e Hidrofílicas; Unión Proteica

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Técnicas de Cultivo de Célula / Acetaminofén Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Chem Res Toxicol Asunto de la revista: TOXICOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Alemania

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