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Pembrolizumab versus placebo as adjuvant therapy in resected stage IIB or IIC melanoma (KEYNOTE-716): distant metastasis-free survival results of a multicentre, double-blind, randomised, phase 3 trial.
Long, Georgina V; Luke, Jason J; Khattak, Muhammad A; de la Cruz Merino, Luis; Del Vecchio, Michele; Rutkowski, Piotr; Spagnolo, Francesco; Mackiewicz, Jacek; Chiarion-Sileni, Vanna; Kirkwood, John M; Robert, Caroline; Grob, Jean-Jacques; de Galitiis, Federica; Schadendorf, Dirk; Carlino, Matteo S; Mohr, Peter; Dummer, Reinhard; Gershenwald, Jeffrey E; Yoon, Charles H; Wu, Xi Lawrence; Fukunaga-Kalabis, Mizuho; Krepler, Clemens; Eggermont, Alexander M M; Ascierto, Paolo A.
Afiliación
  • Long GV; Melanoma Institute Australia, The University of Sydney, Sydney, NSW, Australia; Royal North Shore & Mater Hospitals, Sydney, NSW, Australia. Electronic address: georgina.long@sydney.edu.au.
  • Luke JJ; Department of Medicine, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
  • Khattak MA; Fiona Stanley Hospital, Perth, WA, Australia; Edith Cowan University, Perth, WA, Australia.
  • de la Cruz Merino L; Medical Oncology Department, Hospital Universitario Virgen Macarena, Seville, Spain.
  • Del Vecchio M; Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.
  • Rutkowski P; Department of Soft Tissue, Bone Sarcoma, and Melanoma, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
  • Spagnolo F; IRCCS San Martino Polyclinic Hospital, Genoa, Italy.
  • Mackiewicz J; Department of Medical and Experimental Oncology, Poznan University of Medical Sciences, Poznan, Poland; Department of Diagnostics and Cancer Immunology, Greater Poland Cancer Center, Poznan, Poland.
  • Chiarion-Sileni V; Istituto Oncologico Veneto, IOV-IRCCS, Padova, Italy.
  • Kirkwood JM; Department of Medicine, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
  • Robert C; Department of Dermatology, Institut Gustave Roussy, Villejuif, France; Paris-Saclay University, Villejuif, France.
  • Grob JJ; AP-HM Hospital, Aix-Marseille University, Marseille, France.
  • de Galitiis F; Department of Oncology and Dermatological Oncology, Dermopathic Institute of the Immaculate IDI-IRCCS, Rome, Italy.
  • Schadendorf D; Department of Dermatology, University Hospital Essen & German Cancer Consortium Partner Site, Essen, Germany.
  • Carlino MS; Melanoma Institute Australia, The University of Sydney, Sydney, NSW, Australia; Westmead and Blacktown Hospitals, Sydney, NSW, Australia.
  • Mohr P; Elbe Kliniken Buxtehude, Buxtehude, Germany.
  • Dummer R; University Hospital Zürich Skin Cancer Center, Zürich, Switzerland.
  • Gershenwald JE; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Yoon CH; Department of Surgery, Dana-Farber/Brigham and Women's Cancer Center, Boston, MA, USA.
  • Wu XL; Merck & Co, Rahway, NJ, USA.
  • Fukunaga-Kalabis M; Merck & Co, Rahway, NJ, USA.
  • Krepler C; Merck & Co, Rahway, NJ, USA.
  • Eggermont AMM; University Medical Center Utrecht & Princess Máxima Center, Utrecht, Netherlands; Comprehensive Cancer Center Munich, Munich, Germany.
  • Ascierto PA; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
Lancet Oncol ; 23(11): 1378-1388, 2022 11.
Article en En | MEDLINE | ID: mdl-36265502
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Neoplasias Testiculares / Melanoma Tipo de estudio: Clinical_trials Límite: Child / Humans / Male Idioma: En Revista: Lancet Oncol Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Neoplasias Testiculares / Melanoma Tipo de estudio: Clinical_trials Límite: Child / Humans / Male Idioma: En Revista: Lancet Oncol Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article