Rational design of a Nivolumab-based ANTI-PD-1 single chain variable fragment that blocks the interaction between PD-1 expressed on T-CELLS and PD-L1 ON CHO cells.

Shin, Jong; Raissi, Siavash; Phelan, Paul; Bullock, Peter A

Shin, Jong; Raissi, Siavash; Phelan, Paul; Bullock, Peter A.

Afiliación

Shin J; Department of Pathology, New York University Grossman School of Medicine, 550 First Avenue, New York, NY, 10016, USA.
Raissi S; Department of Developmental, Molecular and Chemical Biology Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA, 02111, USA.
Phelan P; Joinn Biologics, 2600 Hilltop Drive, Building L, Richmond, CA, 94806, USA.
Bullock PA; Department of Developmental, Molecular and Chemical Biology Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA, 02111, USA. Electronic address: Peter.Bullock@tufts.edu.

Protein Expr Purif ; 202: 106196, 2023 02.

Article en En | MEDLINE | ID: mdl-36280166

Asunto(s)

Antígeno B7-H1; Anticuerpos de Cadena Única; Cricetinae; Animales; Humanos; Antígeno B7-H1/genética; Anticuerpos de Cadena Única/genética; Anticuerpos de Cadena Única/farmacología; Anticuerpos de Cadena Única/química; Nivolumab/farmacología; Células CHO; Cricetulus; Anticuerpos Monoclonales/genética

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Anticuerpos de Cadena Única / Antígeno B7-H1 Límite: Animals / Humans Idioma: En Revista: Protein Expr Purif Asunto de la revista: BIOLOGIA MOLECULAR Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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