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Unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses.
Mao, Tianyang; Israelow, Benjamin; Peña-Hernández, Mario A; Suberi, Alexandra; Zhou, Liqun; Luyten, Sophia; Reschke, Melanie; Dong, Huiping; Homer, Robert J; Saltzman, W Mark; Iwasaki, Akiko.
Afiliación
  • Mao T; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Israelow B; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Peña-Hernández MA; Section of Infectious Diseases, Department of Medicine, Yale University School of Medicine, New Haven, CT, USA.
  • Suberi A; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Zhou L; Department of Biomedical Engineering, Yale University, New Haven, CT, USA.
  • Luyten S; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Reschke M; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Dong H; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
  • Homer RJ; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Saltzman WM; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.
  • Iwasaki A; Department of Biomedical Engineering, Yale University, New Haven, CT, USA.
Science ; 378(6622): eabo2523, 2022 11 25.
Article en En | MEDLINE | ID: mdl-36302057
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Inmunidad Mucosa / Glicoproteína de la Espiga del Coronavirus / Vacunas contra la COVID-19 / SARS-CoV-2 / COVID-19 / Células B de Memoria / Células T de Memoria / Memoria Inmunológica Límite: Animals Idioma: En Revista: Science Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Inmunidad Mucosa / Glicoproteína de la Espiga del Coronavirus / Vacunas contra la COVID-19 / SARS-CoV-2 / COVID-19 / Células B de Memoria / Células T de Memoria / Memoria Inmunológica Límite: Animals Idioma: En Revista: Science Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos