Parvifloron D-based potential therapy for glioblastoma: Inducing apoptosis <i>via</i> the mitochondria dependent pathway.

Magalhães, Mariana; Domínguez-Martín, Eva María; Jorge, Joana; Gonçalves, Ana Cristina; Díaz-Lanza, Ana María; Manadas, Bruno; Efferth, Thomas; Rijo, Patrícia; Cabral, Célia

Parvifloron D-based potential therapy for glioblastoma: Inducing apoptosis via the mitochondria dependent pathway.

Magalhães, Mariana; Domínguez-Martín, Eva María; Jorge, Joana; Gonçalves, Ana Cristina; Díaz-Lanza, Ana María; Manadas, Bruno; Efferth, Thomas; Rijo, Patrícia; Cabral, Célia.

Afiliación

Magalhães M; PhD Programme in Experimental Biology and Biomedicine, Institute for Interdisciplinary Research (IIIUC), University of Coimbra, Coimbra, Portugal.
Domínguez-Martín EM; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
Jorge J; Coimbra Institute for Clinical and Biomedical Research (iCBR), Clinic Academic Center of Coimbra (CACC), Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
Gonçalves AC; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal.
Díaz-Lanza AM; CBIOS-Universidade Lusófona's Research Center for Biosciences & Health Technologies, Lisbon, Portugal.
Manadas B; Departamento de Ciencias Biomédicas, Facultad de Farmacia, Universidad de Alcalá de Henares, Madrid, Spain.
Efferth T; Laboratory of Oncobiology and Hematology, University Clinic of Hematology and Applied Molecular Biology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
Rijo P; iCBR, Group of Environment Genetics and Oncobiology (CIMAGO)-Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
Cabral C; Laboratory of Oncobiology and Hematology, University Clinic of Hematology and Applied Molecular Biology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.

Front Pharmacol ; 13: 1006832, 2022.

Article en En | MEDLINE | ID: mdl-36313298

Palabras clave

Plectranthus spp.; abietane diterpenes; antitumor activity; glioblastoma; molecular mechanisms

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Front Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: Portugal