Repurposable Drugs That Interact with Steroid Responsive Gene Targets for Inner Ear Disease.

Missner, Alexander A; Johns, James Dixon; Gu, Shoujun; Hoa, Michael

Missner, Alexander A; Johns, James Dixon; Gu, Shoujun; Hoa, Michael.

Afiliación

Missner AA; Georgetown University School of Medicine, Washington, DC 20007, USA.
Johns JD; Department of Otolaryngology-Head and Neck Surgery, Georgetown University Medical Center, Washington, DC 20007, USA.
Gu S; Auditory Development and Restoration Program, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD 20892, USA.
Hoa M; Department of Otolaryngology-Head and Neck Surgery, Georgetown University Medical Center, Washington, DC 20007, USA.

Biomolecules ; 12(11)2022 11 05.

Article en En | MEDLINE | ID: mdl-36358991

Asunto(s)

Pérdida Auditiva Súbita; Enfermedades del Laberinto; Enfermedad de Meniere; Humanos; Enfermedades del Laberinto/tratamiento farmacológico; Enfermedades del Laberinto/genética; Enfermedad de Meniere/genética; Corticoesteroides; Esteroides/uso terapéutico

Palabras clave

Meniere's disease; RNA sequencing; autoimmune inner ear disease; cochlea; corticosteroids; drug repurposing; spiral ganglion neurons; stria vascularis; sudden sensorineural hearing loss; transcriptome; transtympanic steroids

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pérdida Auditiva Súbita / Enfermedades del Laberinto / Enfermedad de Meniere Límite: Humans Idioma: En Revista: Biomolecules Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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