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Carbon-11-Labeled Methionine PET/CT in Patients With FDG-Occult Multiple Myeloma: A Prospective Pilot Study.
Wang, Yingbing; Yee, Andrew; Bernstein, Zachary; O'Donnell, Elizabeth; Raje, Noopur; Mahmood, Umar.
Afiliación
  • Wang Y; Department of Radiology, Massachusetts General Hospital, 55 Fruit St, Wht 4-427, Boston, MA 02114.
  • Yee A; Center for Multiple Myeloma, Massachusetts General Hospital, Boston, MA.
  • Bernstein Z; Center for Multiple Myeloma, Massachusetts General Hospital, Boston, MA.
  • O'Donnell E; Center for Multiple Myeloma, Massachusetts General Hospital, Boston, MA.
  • Raje N; Center for Multiple Myeloma, Massachusetts General Hospital, Boston, MA.
  • Mahmood U; Department of Radiology, Massachusetts General Hospital, 55 Fruit St, Wht 4-427, Boston, MA 02114.
AJR Am J Roentgenol ; 220(4): 578-579, 2023 04.
Article en En | MEDLINE | ID: mdl-36382911
In a pilot study (ClinicalTrials.gov NCT02646085), seven patients with treated multiple myeloma and negative FDG PET/CT underwent amino acid imaging with 11C-methionine PET/CT. In five participants, 11C-methionine PET/CT showed focal uptake corresponding with lytic lesions; two to 18 lesions were found (SUVmax, 2.8-6.4). Findings indicated a potential role for 11C-methionine PET/CT in detecting residual disease after negative FDG PET/CT, thereby guiding further treatment.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Tomografía Computarizada por Tomografía de Emisión de Positrones / Mieloma Múltiple Límite: Humans Idioma: En Revista: AJR Am J Roentgenol Año: 2023 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Tomografía Computarizada por Tomografía de Emisión de Positrones / Mieloma Múltiple Límite: Humans Idioma: En Revista: AJR Am J Roentgenol Año: 2023 Tipo del documento: Article