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POLθ prevents MRE11-NBS1-CtIP-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps.
Mann, Anjali; Ramirez-Otero, Miguel Angel; De Antoni, Anna; Hanthi, Yodhara Wijesekara; Sannino, Vincenzo; Baldi, Giorgio; Falbo, Lucia; Schrempf, Anna; Bernardo, Sara; Loizou, Joanna; Costanzo, Vincenzo.
Afiliación
  • Mann A; IFOM ETS, The AIRC Institute of Molecular Oncology, Milan, Italy; Department of Oncology and Hematology-Oncology, University of Milan, Milan, Italy.
  • Ramirez-Otero MA; IFOM ETS, The AIRC Institute of Molecular Oncology, Milan, Italy; Department of Oncology and Hematology-Oncology, University of Milan, Milan, Italy.
  • De Antoni A; IFOM ETS, The AIRC Institute of Molecular Oncology, Milan, Italy.
  • Hanthi YW; IFOM ETS, The AIRC Institute of Molecular Oncology, Milan, Italy; Department of Oncology and Hematology-Oncology, University of Milan, Milan, Italy.
  • Sannino V; IFOM ETS, The AIRC Institute of Molecular Oncology, Milan, Italy; Department of Oncology and Hematology-Oncology, University of Milan, Milan, Italy.
  • Baldi G; IFOM ETS, The AIRC Institute of Molecular Oncology, Milan, Italy; Department of Oncology and Hematology-Oncology, University of Milan, Milan, Italy.
  • Falbo L; IFOM ETS, The AIRC Institute of Molecular Oncology, Milan, Italy; Department of Oncology and Hematology-Oncology, University of Milan, Milan, Italy.
  • Schrempf A; Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria.
  • Bernardo S; Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria.
  • Loizou J; Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria.
  • Costanzo V; IFOM ETS, The AIRC Institute of Molecular Oncology, Milan, Italy; Department of Oncology and Hematology-Oncology, University of Milan, Milan, Italy. Electronic address: vincenzo.costanzo@ifom.eu.
Mol Cell ; 82(22): 4218-4231.e8, 2022 11 17.
Article en En | MEDLINE | ID: mdl-36400008
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas de Unión al ADN / Replicación del ADN Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article País de afiliación: Italia
Texto completo
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XML
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas de Unión al ADN / Replicación del ADN Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article País de afiliación: Italia