Novel Thioether-Bridged 2,6-Disubstituted and 2,5,6-Trisubstituted Imidazothiadiazole Analogues: Synthesis, Antiproliferative Activity, ADME, and Molecular Docking Studies.

Ozcan, Ibrahim; Akkoc, Senem; Alici, Hakan; Capanlar, Seval; Sahin, Onur; Tahtaci, Hakan

Ozcan, Ibrahim; Akkoc, Senem; Alici, Hakan; Capanlar, Seval; Sahin, Onur; Tahtaci, Hakan.

Afiliación

Ozcan I; Karabuk University, Faculty of Science, Department of Chemistry, 78050, Karabuk, Türkiye.
Akkoc S; Süleyman Demirel University, Faculty of Pharmacy, Department of Basic Pharmaceutical Sciences, 32260, Isparta, Türkiye.
Alici H; Bahcesehir University, Faculty of Engineering and Natural Sciences, 34353, Istanbul, Türkiye.
Capanlar S; Zonguldak Bülent Ecevit University, Faculty of Science, Department of Physics, 67100, Zonguldak, Türkiye.
Sahin O; Zonguldak Bülent Ecevit University, Faculty of Science, Department of Chemistry, 67100, Zonguldak, Türkiye.
Tahtaci H; Sinop University, Faculty of Health Sciences, Department of Occupational Health & Safety, 57000, Sinop, Türkiye.

Chem Biodivers ; 20(1): e202200884, 2023 Jan.

Article en En | MEDLINE | ID: mdl-36445849

Asunto(s)

Antineoplásicos; Sulfuros; Simulación del Acoplamiento Molecular; Relación Estructura-Actividad; Espectroscopía Infrarroja por Transformada de Fourier; Antineoplásicos/química

Palabras clave

ADME; antiproliferative activity; bioorganic chemistry; cytotoxicity; heterocycles

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Sulfuros / Antineoplásicos Idioma: En Revista: Chem Biodivers Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2023 Tipo del documento: Article

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