Are health outcomes in the older colorectal cancer patients treated by curative intent surgery any different to the younger patients?
ANZ J Surg
; 93(5): 1185-1189, 2023 05.
Article
en En
| MEDLINE
| ID: mdl-36468815
ABSTRACT
BACKGROUND:
Colorectal cancer poses a major burden. Its incidence increases with age and older patients with comorbidities have a higher likelihood of major complications. This study investigated the impact of age on health outcomes in colorectal cancer patients treated by surgery.METHODS:
A prospective database of all patients undergoing colorectal cancer surgery with curative intent between 2012 and 2017 was used to identify patients. A retrospective review of existing medical records investigating health-related outcomes in colorectal cancer patients undergoing surgery was performed. Primary outcomes measured were overall survival (OS) and disease-free survival (DFS). Difference in restricted mean survival times (RMST) up to a pre-specified time point of 24 months was used to compare four age groups.RESULTS:
Six-hundred and fifty-one patients were divided into four age group categories ≤65-years (n = 244), 66 to 75-years (n = 213), 76 to 85-years (n = 162) and >85-years (n = 32). Older patients were found to have a higher rate of post-operative medical complications (including confusion) (P = 0.001) and a longer length of stay (LOS) (P = 0.01). There was no difference between the 76 to 85-year age group and >85-year age group in OS and DFS. However, there was a reduced OS in older patients (>65) compared to their younger cohorts (<65) (P = 0.04).CONCLUSION:
Older patients who undergo curative surgery have reduced OS, increased LOS and higher complication rates. Complex older patients may benefit from geriatric assessment and management in the peri-operative period.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Complicaciones Posoperatorias
/
Neoplasias Colorrectales
Límite:
Aged
/
Humans
Idioma:
En
Revista:
ANZ J Surg
Año:
2023
Tipo del documento:
Article
País de afiliación:
Australia