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Transcriptomic-based evaluation of trichloroethylene glutathione and cysteine conjugates demonstrate phenotype-dependent stress responses in a panel of human in vitro models.
Capinha, Liliana; Zhang, Yaran; Holzer, Anna-Katharina; Ückert, Anna-Katharina; Zana, Melinda; Carta, Giada; Murphy, Cormac; Baldovini, Jenna; Mazidi, Zahra; Grillari, Johannes; Dinnyes, Andras; van de Water, Bob; Leist, Marcel; Commandeur, Jan N M; Jennings, Paul.
Afiliación
  • Capinha L; Division of Molecular and Computational Toxicology, Amsterdam Institute for Molecules, Medicines and Systems, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands. l.santoscapinha@vu.nl.
  • Zhang Y; Division of Molecular and Computational Toxicology, Amsterdam Institute for Molecules, Medicines and Systems, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.
  • Holzer AK; Genomics of Neurodegenerative Diseases and Aging, Human Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.
  • Ückert AK; In Vitro Toxicology and Biomedicine, Dept Inaugurated By the Doerenkamp-Zbinden Foundation, University of Konstanz, 78457, Constance, Germany.
  • Zana M; In Vitro Toxicology and Biomedicine, Dept Inaugurated By the Doerenkamp-Zbinden Foundation, University of Konstanz, 78457, Constance, Germany.
  • Carta G; BioTalentum Ltd, Godollo, 2100, Hungary.
  • Murphy C; Division of Molecular and Computational Toxicology, Amsterdam Institute for Molecules, Medicines and Systems, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.
  • Baldovini J; Division of Molecular and Computational Toxicology, Amsterdam Institute for Molecules, Medicines and Systems, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.
  • Mazidi Z; Division of Molecular and Computational Toxicology, Amsterdam Institute for Molecules, Medicines and Systems, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ, Amsterdam, The Netherlands.
  • Grillari J; Evercyte GmbH, Vienna, Austria.
  • Dinnyes A; Department of Biotechnology, Institute of Molecular Biotechnology, BOKU - University of Natural Resource and Life Science (BOKU), Vienna, Austria.
  • van de Water B; Ludwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA, Vienna, Austria.
  • Leist M; BioTalentum Ltd, Godollo, 2100, Hungary.
  • Commandeur JNM; Department of Physiology and Animal Health, Hungarian University of Agriculture and Life Sciences, Institute of Physiology and Animal Nutrition, Gödöllo, 2100, Hungary.
  • Jennings P; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Leiden, The Netherlands.
Arch Toxicol ; 97(2): 523-545, 2023 Feb.
Article en En | MEDLINE | ID: mdl-36576512
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Tricloroetileno / Células Madre Pluripotentes Inducidas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Arch Toxicol Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Tricloroetileno / Células Madre Pluripotentes Inducidas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Arch Toxicol Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos