Single-nuclei transcriptome analysis of Huntington disease iPSC and mouse astrocytes implicates maturation and functional deficits.

Reyes-Ortiz, Andrea M; Abud, Edsel M; Burns, Mara S; Wu, Jie; Hernandez, Sarah J; McClure, Nicolette; Wang, Keona Q; Schulz, Corey J; Miramontes, Ricardo; Lau, Alice; Michael, Neethu; Miyoshi, Emily; Van Vactor, David; Reidling, John C; Blurton-Jones, Mathew; Swarup, Vivek; Poon, Wayne W; Lim, Ryan G; Thompson, Leslie M

Reyes-Ortiz, Andrea M; Abud, Edsel M; Burns, Mara S; Wu, Jie; Hernandez, Sarah J; McClure, Nicolette; Wang, Keona Q; Schulz, Corey J; Miramontes, Ricardo; Lau, Alice; Michael, Neethu; Miyoshi, Emily; Van Vactor, David; Reidling, John C; Blurton-Jones, Mathew; Swarup, Vivek; Poon, Wayne W; Lim, Ryan G; Thompson, Leslie M.

Afiliación

Reyes-Ortiz AM; Department of Biological Chemistry, University of California, Irvine, Irvine, CA 92617, USA.
Abud EM; Department of Neurobiology & Behavior, University of California, Irvine, Irvine, CA 92617, USA.
Burns MS; Department of Neurobiology & Behavior, University of California, Irvine, Irvine, CA 92617, USA.
Wu J; Department of Biological Chemistry, University of California, Irvine, Irvine, CA 92617, USA.
Hernandez SJ; Department of Neurobiology & Behavior, University of California, Irvine, Irvine, CA 92617, USA.
McClure N; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA 92617, USA.
Wang KQ; Department of Neurobiology & Behavior, University of California, Irvine, Irvine, CA 92617, USA.
Schulz CJ; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA 92617, USA.
Miramontes R; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA 92617, USA.
Lau A; Department of Psychiatry & Human Behavior, University of California, Irvine, Irvine, CA 92617, USA.
Michael N; Department of Neurobiology & Behavior, University of California, Irvine, Irvine, CA 92617, USA.
Miyoshi E; Department of Neurobiology & Behavior, University of California, Irvine, Irvine, CA 92617, USA.
Van Vactor D; Harvard Medical School, Department of Cell Biology, Boston, MA 02115, USA.
Reidling JC; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA 92617, USA.
Blurton-Jones M; Department of Neurobiology & Behavior, University of California, Irvine, Irvine, CA 92617, USA.
Swarup V; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA 92617, USA.
Poon WW; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA 92617, USA.
Lim RG; Department of Neurobiology & Behavior, University of California, Irvine, Irvine, CA 92617, USA.
Thompson LM; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA 92617, USA.

iScience ; 26(1): 105732, 2023 Jan 20.

Article en En | MEDLINE | ID: mdl-36590162

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Neurology; Omics

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: IScience Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos