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De-erosion of X chromosome dosage compensation by the editing of XIST regulatory regions restores the differentiation potential in hPSCs.
Motosugi, Nami; Sugiyama, Akiko; Okada, Chisa; Otomo, Asako; Umezawa, Akihiro; Akutsu, Hidenori; Hadano, Shinji; Fukuda, Atsushi.
Afiliación
  • Motosugi N; Department of Molecular Life Sciences, Division of Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
  • Sugiyama A; Department of Molecular Life Sciences, Division of Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
  • Okada C; Support Center for Medical Research and Education, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
  • Otomo A; Department of Molecular Life Sciences, Division of Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
  • Umezawa A; The Institute of Medical Sciences, Tokai University, Isehara, Kanagawa, Japan.
  • Akutsu H; Micro/Nano Technology Center, Tokai University, Hiratsuka, Kanagawa, Japan.
  • Hadano S; Center for Regenerative Medicine, National Center for Child Health and Development, Tokyo, Japan.
  • Fukuda A; Center for Regenerative Medicine, National Center for Child Health and Development, Tokyo, Japan.
Cell Rep Methods ; 2(12): 100352, 2022 12 19.
Article en En | MEDLINE | ID: mdl-36590687
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Cromosoma X / Células Madre Pluripotentes / ARN Largo no Codificante Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Cell Rep Methods Año: 2022 Tipo del documento: Article País de afiliación: Japón
Texto completo
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PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Cromosoma X / Células Madre Pluripotentes / ARN Largo no Codificante Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Cell Rep Methods Año: 2022 Tipo del documento: Article País de afiliación: Japón