Polyethyleneimine-induced fluorescence enhancement strategy for AIEgen: the mechanism and application.
Anal Bioanal Chem
; 415(7): 1347-1355, 2023 Mar.
Article
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| MEDLINE
| ID: mdl-36693956
ABSTRACT
Aggregation-induced emission luminogens (AIEgens) are attracting extensive research attention in the biosensor fields. Herein, we report a new polyethyleneimine (PEI)-induced strategy for enhancing luminescence of TCBPE (an AIEgen) to promote its development in biosensor. The copolymer dots (TCBPE-PEI) with high quantum yield (39.7%) and outstanding stability were synthesized via a one-pot method. The fluorescence enhancement mechanism based on the PEI strategy originated from the restriction of intramolecular motions of TCBPEs and the form of donor-acceptor structures to decrease the inherent energy bandgap. Benefiting from chelating property of TCBPE-PEI by Cu2+, a fluorescence-quenching sensor for Cu2+ detection was developed based on the fluorescence quenching of the electron transfer effect. Especially, a good linear range of 10-250 nM with a low limit of detection 1.1 nM was achieved, and it was further applied in samples successfully. The current work provides a novel approach to fabricate AIEgen biosensors and shows great potential in Cu2+ detection.
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MEDLINE
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En
Revista:
Anal Bioanal Chem
Año:
2023
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Article
País de afiliación:
China