Pathogenic Mechanisms of Pulmonary Arterial Hypertension: Homeostasis Imbalance of Endothelium-Derived Relaxing and Contracting Factors.

Zhu, Jinsheng; Yang, Lei; Jia, Yangfan; Balistrieri, Angela; Fraidenburg, Dustin R; Wang, Jian; Tang, Haiyang; Yuan, Jason X-J

Zhu, Jinsheng; Yang, Lei; Jia, Yangfan; Balistrieri, Angela; Fraidenburg, Dustin R; Wang, Jian; Tang, Haiyang; Yuan, Jason X-J.

Afiliación

Zhu J; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangdong Key Laboratory of Vascular Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Yang L; College of Veterinary Medicine, Northwest A&F University, Yangling, China.
Jia Y; College of Veterinary Medicine, Northwest A&F University, Yangling, China.
Balistrieri A; Section of Physiology, Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of California, San Diego, La Jolla, California, USA.
Fraidenburg DR; Division of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
Wang J; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangdong Key Laboratory of Vascular Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Tang H; Section of Physiology, Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of California, San Diego, La Jolla, California, USA.
Yuan JX; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangdong Key Laboratory of Vascular Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

JACC Asia ; 2(7): 787-802, 2022 Dec.

Article en En | MEDLINE | ID: mdl-36713766

Palabras clave

5-HT, 5-hydroxytryptamine; ACE, angiotensin-converting enzyme; EC, endothelial cell; EDCF, endothelium-derived contracting factor; EDRF, endothelium-derived relaxing factor; ET, endothelin; PAH, pulmonary arterial hypertension; PASMC, pulmonary artery smooth muscle cell; PG, prostaglandin; TPH, tryptophan hydroxylase; TXA2, thromboxane A2; cGMP, cyclic guanosine monophosphate; endothelial dysfunction; endothelium-derived relaxing factor; pulmonary arterial hypertension; vascular homeostasis

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Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: JACC Asia Año: 2022 Tipo del documento: Article País de afiliación: China

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