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A human liver organoid screening platform for DILI risk prediction.
Zhang, Charles J; Meyer, Sophia R; O'Meara, Matthew J; Huang, Sha; Capeling, Meghan M; Ferrer-Torres, Daysha; Childs, Charlie J; Spence, Jason R; Fontana, Robert J; Sexton, Jonathan Z.
Afiliación
  • Zhang CJ; Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, 48109, USA.
  • Meyer SR; Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, 48109, USA.
  • O'Meara MJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 48109, USA.
  • Huang S; Department of Internal Medicine, Gastroenterology and Hepatology, Michigan Medicine at the University of Michigan, Ann Arbor, MI, 48109, USA.
  • Capeling MM; Department of Internal Medicine, Gastroenterology and Hepatology, Michigan Medicine at the University of Michigan, Ann Arbor, MI, 48109, USA.
  • Ferrer-Torres D; Department of Internal Medicine, Gastroenterology and Hepatology, Michigan Medicine at the University of Michigan, Ann Arbor, MI, 48109, USA.
  • Childs CJ; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.
  • Spence JR; Department of Internal Medicine, Gastroenterology and Hepatology, Michigan Medicine at the University of Michigan, Ann Arbor, MI, 48109, USA; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.
  • Fontana RJ; Department of Internal Medicine, Gastroenterology and Hepatology, Michigan Medicine at the University of Michigan, Ann Arbor, MI, 48109, USA.
  • Sexton JZ; Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, 48109, USA; Department of Internal Medicine, Gastroenterology and Hepatology, Michigan Medicine at the University of Michigan, Ann Arbor, MI, 48109, USA; U-M Center for Drug Repurposing, University of Mich
J Hepatol ; 78(5): 998-1006, 2023 05.
Article en En | MEDLINE | ID: mdl-36738840
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos / Enfermedad Hepática Inducida por Sustancias y Drogas Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Límite: Humans Idioma: En Revista: J Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos / Enfermedad Hepática Inducida por Sustancias y Drogas Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Límite: Humans Idioma: En Revista: J Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos