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LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice.
Prakasam, Ramachandran; Bonadiman, Angela; Andreotti, Roberta; Zuccaro, Emanuela; Dalfovo, Davide; Marchioretti, Caterina; Tripathy, Debasmita; Petris, Gianluca; Anderson, Eric N; Migazzi, Alice; Tosatto, Laura; Cereseto, Anna; Battaglioli, Elena; Sorarù, Gianni; Lim, Wooi Fang; Rinaldi, Carlo; Sambataro, Fabio; Pourshafie, Naemeh; Grunseich, Christopher; Romanel, Alessandro; Pandey, Udai Bhan; Contestabile, Andrea; Ronzitti, Giuseppe; Basso, Manuela; Pennuto, Maria.
Afiliación
  • Prakasam R; Dulbecco Telethon Institute at the Department of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy.
  • Bonadiman A; Department of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy.
  • Andreotti R; Department of Biomedical Sciences, University of Padova, Padova, Italy.
  • Zuccaro E; Veneto Institute of Molecular Medicine, Padova, Italy.
  • Dalfovo D; Padova Neuroscience Center, Padova, Italy.
  • Marchioretti C; Department of Biomedical Sciences, University of Padova, Padova, Italy.
  • Tripathy D; Veneto Institute of Molecular Medicine, Padova, Italy.
  • Petris G; Padova Neuroscience Center, Padova, Italy.
  • Anderson EN; Department of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy.
  • Migazzi A; Department of Biomedical Sciences, University of Padova, Padova, Italy.
  • Tosatto L; Veneto Institute of Molecular Medicine, Padova, Italy.
  • Cereseto A; Padova Neuroscience Center, Padova, Italy.
  • Battaglioli E; Department of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy.
  • Sorarù G; Department of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy.
  • Lim WF; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.
  • Rinaldi C; Wellcome Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Saffron Walden, UK.
  • Sambataro F; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
  • Pourshafie N; Dulbecco Telethon Institute at the Department of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy.
  • Grunseich C; Department of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy.
  • Romanel A; Dulbecco Telethon Institute at the Department of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy.
  • Pandey UB; Department of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy.
  • Contestabile A; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.
  • Ronzitti G; Padova Neuroscience Center, Padova, Italy.
  • Basso M; Department of Neuroscience, University of Padova, Padova, Italy.
  • Pennuto M; MDUK Oxford Neuromuscular Centre, University of Oxford, Oxford, UK.
Nat Commun ; 14(1): 603, 2023 02 06.
Article en En | MEDLINE | ID: mdl-36746939
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Trastornos Musculares Atróficos / Dípteros / Atrofia Bulboespinal Ligada al X Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Italia
Texto completo
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XML
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Trastornos Musculares Atróficos / Dípteros / Atrofia Bulboespinal Ligada al X Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Italia