STAT3 protects HSCs from intrinsic interferon signaling and loss of long-term blood-forming activity.

Patel, Bhakti; Zhou, Yifan; Babcock, Rachel L; Ma, Feiyang; Zal, Malgorzata A; Kumar, Dhiraj; Medik, Yusra B; Kahn, Laura M; Pineda, Josué E; Park, Elizabeth M; Tang, Ximing; Raso, Maria Gabriela; Zal, Tomasz; Clise-Dwyer, Karen; Giancotti, Filippo G; Colla, Simona; Watowich, Stephanie S

Patel, Bhakti; Zhou, Yifan; Babcock, Rachel L; Ma, Feiyang; Zal, Malgorzata A; Kumar, Dhiraj; Medik, Yusra B; Kahn, Laura M; Pineda, Josué E; Park, Elizabeth M; Tang, Ximing; Raso, Maria Gabriela; Zal, Tomasz; Clise-Dwyer, Karen; Giancotti, Filippo G; Colla, Simona; Watowich, Stephanie S.

Afiliación

Patel B; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Zhou Y; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Babcock RL; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Ma F; MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA.
Zal MA; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, USA.
Kumar D; Division of Rheumatology, Department of Internal Medicine, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA.
Medik YB; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Kahn LM; Herbert Irving Cancer Center and Department of Genetics and Development, Columbia University, New York, NY, USA.
Pineda JE; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Park EM; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Tang X; MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA.
Raso MG; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Zal T; MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA.
Clise-Dwyer K; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Giancotti FG; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Colla S; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Watowich SS; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

bioRxiv ; 2023 Feb 11.

Article en En | MEDLINE | ID: mdl-36798265

Palabras clave

DNA damage; IFN signaling; STAT3; cell cycle; hematopoietic stem cell

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: BioRxiv Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos