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Synthesis of highly substituted isoquinolines/isoquinolones by ruthenium (II)-catalyzed reaction of benzyl/α-methyl benzyl/benzoyl isocyanates with diaryl alkynes.
Kumar, Amrendra; Jaiswal, Shubham; Tadigoppula, Narender.
Afiliación
  • Kumar A; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India. t_narendra@cdri.res.in.
  • Jaiswal S; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India. t_narendra@cdri.res.in.
  • Tadigoppula N; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh-201 002, India.
Chem Commun (Camb) ; 59(20): 2970-2973, 2023 Mar 07.
Article en En | MEDLINE | ID: mdl-36806825
An efficient and novel method has been developed for the synthesis of highly substituted isoquinolines/isoquinolones by Ru(II)-catalyzed intermolecular oxidative annulation of benzyl/benzoyl isocyanates with diaryl alkynes in the presence of Cs2CO3 as base and Cu(OTf)2 as an oxidant at 120 °C for 1 h.
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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: India
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: India