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The structure of pathogenic huntingtin exon 1 defines the bases of its aggregation propensity.
Elena-Real, Carlos A; Sagar, Amin; Urbanek, Annika; Popovic, Matija; Morató, Anna; Estaña, Alejandro; Fournet, Aurélie; Doucet, Christine; Lund, Xamuel L; Shi, Zhen-Dan; Costa, Luca; Thureau, Aurélien; Allemand, Frédéric; Swenson, Rolf E; Milhiet, Pierre-Emmanuel; Crehuet, Ramon; Barducci, Alessandro; Cortés, Juan; Sinnaeve, Davy; Sibille, Nathalie; Bernadó, Pau.
Afiliación
  • Elena-Real CA; Centre for Structural Biology, University of Montpellier, INSERM, CNRS, Montpellier, France.
  • Sagar A; Centre for Structural Biology, University of Montpellier, INSERM, CNRS, Montpellier, France.
  • Urbanek A; Centre for Structural Biology, University of Montpellier, INSERM, CNRS, Montpellier, France.
  • Popovic M; Centre for Structural Biology, University of Montpellier, INSERM, CNRS, Montpellier, France.
  • Morató A; Centre for Structural Biology, University of Montpellier, INSERM, CNRS, Montpellier, France.
  • Estaña A; Centre for Structural Biology, University of Montpellier, INSERM, CNRS, Montpellier, France.
  • Fournet A; LAAS-CNRS, University of Toulouse, CNRS, Toulouse, France.
  • Doucet C; Centre for Structural Biology, University of Montpellier, INSERM, CNRS, Montpellier, France.
  • Lund XL; Centre for Structural Biology, University of Montpellier, INSERM, CNRS, Montpellier, France.
  • Shi ZD; Centre for Structural Biology, University of Montpellier, INSERM, CNRS, Montpellier, France.
  • Costa L; Institute of Laue Langevin, Grenoble, France.
  • Thureau A; The Chemistry and Synthesis Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Rockville, MD, USA.
  • Allemand F; Centre for Structural Biology, University of Montpellier, INSERM, CNRS, Montpellier, France.
  • Swenson RE; SWING Beamline, Synchrotron SOLEIL, Gif sur Yvette, France.
  • Milhiet PE; Centre for Structural Biology, University of Montpellier, INSERM, CNRS, Montpellier, France.
  • Crehuet R; The Chemistry and Synthesis Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Rockville, MD, USA.
  • Barducci A; Centre for Structural Biology, University of Montpellier, INSERM, CNRS, Montpellier, France.
  • Cortés J; Institute for Advanced Chemistry of Catalonia (IQAC), CSIC, Barcelona, Spain.
  • Sinnaeve D; Centre for Structural Biology, University of Montpellier, INSERM, CNRS, Montpellier, France.
  • Sibille N; LAAS-CNRS, University of Toulouse, CNRS, Toulouse, France.
  • Bernadó P; Univ. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1167 - RID-AGE - Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.
Nat Struct Mol Biol ; 30(3): 309-320, 2023 03.
Article en En | MEDLINE | ID: mdl-36864173

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Exones Idioma: En Revista: Nat Struct Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2023 Tipo del documento: Article País de afiliación: Francia

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Exones Idioma: En Revista: Nat Struct Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2023 Tipo del documento: Article País de afiliación: Francia