GPR116 receptor regulates the antitumor function of NK cells via G&#945;q/HIF1&#945;/NF-&#954;B signaling pathway as a potential immune checkpoint.

Guo, Dandan; Jin, Chenxu; Gao, Yaoxin; Lin, Haizhen; Zhang, Li; Zhou, Ying; Yao, Jie; Duan, Yixin; Ren, Yaojun; Hui, Xinhui; Ge, Yujia; Yang, Renzheng; Jiang, Wenzheng

GPR116 receptor regulates the antitumor function of NK cells via Gαq/HIF1α/NF-κB signaling pathway as a potential immune checkpoint.

Guo, Dandan; Jin, Chenxu; Gao, Yaoxin; Lin, Haizhen; Zhang, Li; Zhou, Ying; Yao, Jie; Duan, Yixin; Ren, Yaojun; Hui, Xinhui; Ge, Yujia; Yang, Renzheng; Jiang, Wenzheng.

Afiliación

Guo D; Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, 500 Dongchuan Rood, Shanghai, 200241, China.
Jin C; Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, 500 Dongchuan Rood, Shanghai, 200241, China.
Gao Y; Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, 500 Dongchuan Rood, Shanghai, 200241, China.
Lin H; Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, 500 Dongchuan Rood, Shanghai, 200241, China.
Zhang L; Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, 500 Dongchuan Rood, Shanghai, 200241, China.
Zhou Y; Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, 500 Dongchuan Rood, Shanghai, 200241, China.
Yao J; Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, 500 Dongchuan Rood, Shanghai, 200241, China.
Duan Y; Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, 500 Dongchuan Rood, Shanghai, 200241, China.
Ren Y; Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, 500 Dongchuan Rood, Shanghai, 200241, China.
Hui X; Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, 500 Dongchuan Rood, Shanghai, 200241, China.
Ge Y; Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, 500 Dongchuan Rood, Shanghai, 200241, China.
Yang R; Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, 500 Dongchuan Rood, Shanghai, 200241, China.
Jiang W; Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, 500 Dongchuan Rood, Shanghai, 200241, China. wzjiang@bio.ecnu.edu.cn.

Cell Biosci ; 13(1): 51, 2023 Mar 09.

Article en En | MEDLINE | ID: mdl-36895027

Palabras clave

GPR116; HIF1α; Immunotherapy; NK; NK-κB

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Cell Biosci Año: 2023 Tipo del documento: Article País de afiliación: China