Chitinase 3 like 1 deficiency ameliorates lipopolysaccharide-induced acute liver injury by inhibition of M2 macrophage polarization.

Kim, Minji; Chang, Ju Young; Lee, Dong Won; Kim, Yu Ri; Son, Dong Ju; Yun, Jaesuk; Jung, Young Suk; Lee, Dong Hun; Han, Sangbae; Hong, Jin Tae

Kim, Minji; Chang, Ju Young; Lee, Dong Won; Kim, Yu Ri; Son, Dong Ju; Yun, Jaesuk; Jung, Young Suk; Lee, Dong Hun; Han, Sangbae; Hong, Jin Tae.

Afiliación

Kim M; College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro 194-31, Osong-eup, Heungduk-gu, Cheongju, Chungbuk 361-951, Republic of Korea.
Chang JY; College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro 194-31, Osong-eup, Heungduk-gu, Cheongju, Chungbuk 361-951, Republic of Korea.
Lee DW; College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro 194-31, Osong-eup, Heungduk-gu, Cheongju, Chungbuk 361-951, Republic of Korea.
Kim YR; College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro 194-31, Osong-eup, Heungduk-gu, Cheongju, Chungbuk 361-951, Republic of Korea.
Son DJ; College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro 194-31, Osong-eup, Heungduk-gu, Cheongju, Chungbuk 361-951, Republic of Korea.
Yun J; College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro 194-31, Osong-eup, Heungduk-gu, Cheongju, Chungbuk 361-951, Republic of Korea.
Jung YS; College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea.
Lee DH; Department of Biological Sciences, College of Natural Sciences, Chonnam National University, Gwangju 61186, Republic of Korea.
Han S; College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro 194-31, Osong-eup, Heungduk-gu, Cheongju, Chungbuk 361-951, Republic of Korea.
Hong JT; College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro 194-31, Osong-eup, Heungduk-gu, Cheongju, Chungbuk 361-951, Republic of Korea. Electronic address: jinthong@chungbuk.ac.kr.

Mol Immunol ; 156: 98-110, 2023 04.

Article en En | MEDLINE | ID: mdl-36921490

Asunto(s)

Quitinasas; Sepsis; Animales; Ratones; Quitinasas/metabolismo; Lipopolisacáridos/toxicidad; Lipopolisacáridos/metabolismo; Hígado/metabolismo; Macrófagos/metabolismo; ARN Mensajero/metabolismo; Sepsis/metabolismo

Palabras clave

CHI3L1; Lipopolysaccharide; M1/M2 polarization; Pro-inflammatory cytokine; Sepsis

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Quitinasas / Sepsis Límite: Animals Idioma: En Revista: Mol Immunol Año: 2023 Tipo del documento: Article