Titanium-doped PET nanoplastics of environmental origin as a true-to-life model of nanoplastic.
Sci Total Environ
; 880: 163151, 2023 Jul 01.
Article
en En
| MEDLINE
| ID: mdl-37011676
ABSTRACT
The increased presence of secondary micro/nanoplastics (MNPLs) in the environment requires urgent studies on their potentially hazardous effects on exposed organisms, including humans. In this context, it is essential to obtain representative MNPL samples for such purposes. In our study, we have obtained true-to-life NPLs resulting from the degradation, via sanding, of opaque PET bottles. Since these bottles contain titanium (TiO2NPs), the resulting MNPLs also contain embedded metal. The obtained PET(Ti)NPLs were extensively characterized from a physicochemical point of view, confirming their nanosized range and their hybrid composition. This is the first time these types of NPLs are obtained and characterized. The preliminary hazard studies show their easy internalization in different cell lines, without apparent general toxicity. The demonstration by confocal microscopy that the obtained NPLs contain Ti samples offers this material multiple advantages. Thus, they can be used in in vivo approaches to determine the fate of NPLs after exposure, escaping from the existing difficulties to follow up MNPLs in biological samples.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Plásticos
/
Microplásticos
Límite:
Humans
Idioma:
En
Revista:
Sci Total Environ
Año:
2023
Tipo del documento:
Article
País de afiliación:
Chile