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Preclinical discovery and initial clinical data of WVT078, a BCMA × CD3 bispecific antibody.
Raab, Marc S; Cohen, Yael C; Schjesvold, Fredrik; Aardalen, Kimberly; Oka, Adwait; Spencer, Andrew; Wermke, Martin; Souza, Anita D; Kaufman, Jonathan L; Cafro, Anna Maria; Ocio, Enrique M; Doki, Noriko; Henson, Kristin; Trabucco, Gina; Carrion, Ana; Bender, Florent C; Juif, Pierre-Eric; Fessehatsion, Adonai; Fan, Liqiong; Stonehouse, Jeffrey P; Blankenship, John W; Granda, Brian; De Vita, Serena; Lu, Haihui.
Afiliación
  • Raab MS; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.
  • Cohen YC; Department of Hematology, Tel-Aviv Sourasky (Ichilov) Medical Center, Tel Aviv University, Tel Aviv, Israel.
  • Schjesvold F; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Aardalen K; Oslo Myeloma Center, Department of Hematology, Oslo University Hospital, Oslo, Norway.
  • Oka A; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Spencer A; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Wermke M; Department of Malignant Haematology, The Alfred Hospital, Melbourne, VIC, Australia.
  • Souza AD; NCT/UCC Early Clinical Trial Unit, Universitätsklinikum Carl Gustav Carus an der Technische Universität, Dresden, Germany.
  • Kaufman JL; Division of Hematology & Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.
  • Cafro AM; Winship Cancer Institute, Emory University, Atlanta, GA, USA.
  • Ocio EM; Department of Hematology, Niguarda Hospital, Niguarda, Milan, Italy.
  • Doki N; Hospital Universitario Marqués de Valdecilla (IDIVAL), Universidad de Cantabria, Santander, Spain.
  • Henson K; Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan.
  • Trabucco G; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Carrion A; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Bender FC; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Juif PE; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Fessehatsion A; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Fan L; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Stonehouse JP; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Blankenship JW; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Granda B; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • De Vita S; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Lu H; Novartis Institutes for BioMedical Research, Cambridge, MA, USA. serena.de_vita@novartis.com.
Leukemia ; 37(6): 1349-1360, 2023 06.
Article en En | MEDLINE | ID: mdl-37024520
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Anticuerpos Biespecíficos / Inmunoconjugados / Mieloma Múltiple Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2023 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Anticuerpos Biespecíficos / Inmunoconjugados / Mieloma Múltiple Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2023 Tipo del documento: Article País de afiliación: Alemania