Dual action anti-inflammatory/antiviral isoquinoline alkaloids as potent naturally occurring anti-SARS-CoV-2 agents: A combined pharmacological and medicinal chemistry perspective.

Valipour, Mehdi; Hosseini, Asieh; Di Sotto, Antonella; Irannejad, Hamid

Valipour, Mehdi; Hosseini, Asieh; Di Sotto, Antonella; Irannejad, Hamid.

Afiliación

Valipour M; Razi Drug Research Center, Iran University of Medical Sciences, Tehran, Iran.
Hosseini A; Razi Drug Research Center, Iran University of Medical Sciences, Tehran, Iran.
Di Sotto A; Department of Physiology and Pharmacology "V. Erspamer", Sapienza University of Rome, Rome, Italy.
Irannejad H; Department of Medicinal Chemistry, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.

Phytother Res ; 37(5): 2168-2186, 2023 May.

Article en En | MEDLINE | ID: mdl-37039761

Asunto(s)

Alcaloides; COVID-19; Humanos; Química Farmacéutica; SARS-CoV-2; Pandemias; Isoquinolinas/farmacología; Isoquinolinas/uso terapéutico; Alcaloides/farmacología; Alcaloides/uso terapéutico; Antiinflamatorios/farmacología; Antiinflamatorios/uso terapéutico; Antivirales/farmacología; Antivirales/uso terapéutico

Palabras clave

COVID-19; Papaverine; anti-inflammatory; emetine; isoquinoline-based alkaloids; p38 MAPK pathway

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Alcaloides / COVID-19 Límite: Humans Idioma: En Revista: Phytother Res Asunto de la revista: TERAPIAS COMPLEMENTARES Año: 2023 Tipo del documento: Article País de afiliación: Irán

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