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The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes.
Huerta-Chagoya, Alicia; Schroeder, Philip; Mandla, Ravi; Deutsch, Aaron J; Zhu, Wanying; Petty, Lauren; Yi, Xiaoyan; Cole, Joanne B; Udler, Miriam S; Dornbos, Peter; Porneala, Bianca; DiCorpo, Daniel; Liu, Ching-Ti; Li, Josephine H; Szczerbinski, Lukasz; Kaur, Varinderpal; Kim, Joohyun; Lu, Yingchang; Martin, Alicia; Eizirik, Decio L; Marchetti, Piero; Marselli, Lorella; Chen, Ling; Srinivasan, Shylaja; Todd, Jennifer; Flannick, Jason; Gubitosi-Klug, Rose; Levitsky, Lynne; Shah, Rachana; Kelsey, Megan; Burke, Brian; Dabelea, Dana M; Divers, Jasmin; Marcovina, Santica; Stalbow, Lauren; Loos, Ruth J F; Darst, Burcu F; Kooperberg, Charles; Raffield, Laura M; Haiman, Christopher; Sun, Quan; McCormick, Joseph B; Fisher-Hoch, Susan P; Ordoñez, Maria L; Meigs, James; Baier, Leslie J; González-Villalpando, Clicerio; González-Villalpando, Maria Elena; Orozco, Lorena; García-García, Lourdes.
Afiliación
  • Huerta-Chagoya A; Programs in Metabolism and Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA. ahuerta@broadinstitute.org.
  • Schroeder P; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA. ahuerta@broadinstitute.org.
  • Mandla R; Departamento de Medicina Genómica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico City, Mexico. ahuerta@broadinstitute.org.
  • Deutsch AJ; Unidad de Biología Molecular y Medicina Genómica, Instituto Nacional de Ciencias Médicas y Nutrición, Mexico City, Mexico. ahuerta@broadinstitute.org.
  • Zhu W; Programs in Metabolism and Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Petty L; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Yi X; Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA.
  • Cole JB; Programs in Metabolism and Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Udler MS; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Dornbos P; Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA.
  • Porneala B; Programs in Metabolism and Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • DiCorpo D; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Liu CT; Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA.
  • Li JH; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Szczerbinski L; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Kaur V; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Kim J; ULB Center for Diabetes Research, Medical Faculty, Université Libre de Bruxelles, Brussels, Belgium.
  • Lu Y; Programs in Metabolism and Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Martin A; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Eizirik DL; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Marchetti P; Division of Endocrinology, Boston Children's Hospital, Boston, MA, USA.
  • Marselli L; Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, CO, USA.
  • Chen L; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Srinivasan S; Programs in Metabolism and Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Todd J; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Flannick J; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
  • Gubitosi-Klug R; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
  • Levitsky L; Programs in Metabolism and Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Shah R; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Kelsey M; Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA.
  • Burke B; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Dabelea DM; Programs in Metabolism and Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Divers J; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Marcovina S; Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA.
  • Stalbow L; Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland.
  • Loos RJF; Clinical Research Centre, Medical University of Bialystok, Bialystok, Poland.
  • Darst BF; Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA.
  • Kooperberg C; Vanderbilt Genetics Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Raffield LM; Vanderbilt Genetics Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Haiman C; Programs in Metabolism and Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Sun Q; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.
  • McCormick JB; ULB Center for Diabetes Research, Medical Faculty, Université Libre de Bruxelles, Brussels, Belgium.
  • Fisher-Hoch SP; WELBIO, Université Libre de Bruxelles, Brussels, Belgium.
  • Ordoñez ML; Department of Clinical and Experimental Medicine, and AOUP Cisanello University Hospital, University of Pisa, Pisa, Italy.
  • Meigs J; Department of Clinical and Experimental Medicine, and AOUP Cisanello University Hospital, University of Pisa, Pisa, Italy.
  • Baier LJ; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • González-Villalpando C; Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA.
  • González-Villalpando ME; Department of Pediatrics, University of Vermont, Burlington, VT, USA.
  • Orozco L; Programs in Metabolism and Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • García-García L; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.
Diabetologia ; 66(7): 1273-1288, 2023 07.
Article en En | MEDLINE | ID: mdl-37148359
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Salud Poblacional Tipo de estudio: Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Diabetologia Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Salud Poblacional Tipo de estudio: Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Diabetologia Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos