Model selection and robust inference of mutational signatures using Negative Binomial non-negative matrix factorization.

Pelizzola, Marta; Laursen, Ragnhild; Hobolth, Asger

Pelizzola, Marta; Laursen, Ragnhild; Hobolth, Asger.

Afiliación

Pelizzola M; Department of Mathematics, Aarhus University, Aarhus, Denmark. marta@math.au.dk.
Laursen R; Department of Mathematics, Aarhus University, Aarhus, Denmark.
Hobolth A; Department of Mathematics, Aarhus University, Aarhus, Denmark.

BMC Bioinformatics ; 24(1): 187, 2023 May 08.

Article en En | MEDLINE | ID: mdl-37158829

Asunto(s)

Algoritmos; Mama; Masculino; Humanos; Mutación; Distribución Binomial; Simulación por Computador

Palabras clave

Cancer genomics; Cross-validation; Model checking; Model selection; Mutational signatures; Negative Binomial; Non-negative matrix factorization; Poisson

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Algoritmos / Mama Tipo de estudio: Prognostic_studies Límite: Humans / Male Idioma: En Revista: BMC Bioinformatics Asunto de la revista: INFORMATICA MEDICA Año: 2023 Tipo del documento: Article País de afiliación: Dinamarca

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