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Uridine-derived ribose fuels glucose-restricted pancreatic cancer.
Nwosu, Zeribe C; Ward, Matthew H; Sajjakulnukit, Peter; Poudel, Pawan; Ragulan, Chanthirika; Kasperek, Steven; Radyk, Megan; Sutton, Damien; Menjivar, Rosa E; Andren, Anthony; Apiz-Saab, Juan J; Tolstyka, Zachary; Brown, Kristee; Lee, Ho-Joon; Dzierozynski, Lindsey N; He, Xi; Ps, Hari; Ugras, Julia; Nyamundanda, Gift; Zhang, Li; Halbrook, Christopher J; Carpenter, Eileen S; Shi, Jiaqi; Shriver, Leah P; Patti, Gary J; Muir, Alexander; Pasca di Magliano, Marina; Sadanandam, Anguraj; Lyssiotis, Costas A.
Afiliación
  • Nwosu ZC; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
  • Ward MH; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
  • Sajjakulnukit P; Department of Chemistry, Washington University in St Louis, St Louis, MO, USA.
  • Poudel P; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.
  • Ragulan C; Center for Metabolomics and Isotope Tracing, Washington University in St Louis, St Louis, MO, USA.
  • Kasperek S; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
  • Radyk M; Division of Molecular Pathology, The Institute of Cancer Research, London, UK.
  • Sutton D; Division of Molecular Pathology, The Institute of Cancer Research, London, UK.
  • Menjivar RE; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
  • Andren A; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
  • Apiz-Saab JJ; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
  • Tolstyka Z; Cellular and Molecular Biology Program, University of Michigan, Ann Arbor, MI, USA.
  • Brown K; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
  • Lee HJ; Ben May Department for Cancer Research, University of Chicago, Chicago, IL, USA.
  • Dzierozynski LN; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
  • He X; Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
  • Ps H; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
  • Ugras J; Ben May Department for Cancer Research, University of Chicago, Chicago, IL, USA.
  • Nyamundanda G; Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
  • Zhang L; Division of Molecular Pathology, The Institute of Cancer Research, London, UK.
  • Halbrook CJ; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
  • Carpenter ES; Division of Molecular Pathology, The Institute of Cancer Research, London, UK.
  • Shi J; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
  • Shriver LP; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
  • Patti GJ; Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA.
  • Muir A; Department of Pathology and Clinical Labs, Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA.
  • Pasca di Magliano M; Department of Chemistry, Washington University in St Louis, St Louis, MO, USA.
  • Sadanandam A; Department of Medicine, Washington University in St Louis, St Louis, MO, USA.
  • Lyssiotis CA; Center for Metabolomics and Isotope Tracing, Washington University in St Louis, St Louis, MO, USA.
Nature ; 618(7963): 151-158, 2023 Jun.
Article en En | MEDLINE | ID: mdl-37198494

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Ribosa / Uridina / Microambiente Tumoral / Glucosa Límite: Animals / Humans Idioma: En Revista: Nature Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Ribosa / Uridina / Microambiente Tumoral / Glucosa Límite: Animals / Humans Idioma: En Revista: Nature Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos