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In vitro selection of macrocyclic peptide inhibitors containing cyclic γ2,4-amino acids targeting the SARS-CoV-2 main protease.
Miura, Takashi; Malla, Tika R; Owen, C David; Tumber, Anthony; Brewitz, Lennart; McDonough, Michael A; Salah, Eidarus; Terasaka, Naohiro; Katoh, Takayuki; Lukacik, Petra; Strain-Damerell, Claire; Mikolajek, Halina; Walsh, Martin A; Kawamura, Akane; Schofield, Christopher J; Suga, Hiroaki.
Afiliación
  • Miura T; Department of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
  • Malla TR; Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, Chemistry Research Laboratory, University of Oxford, Oxford, UK.
  • Owen CD; Diamond Light Source, Harwell Science & Innovation Campus, Didcot, UK.
  • Tumber A; Research Complex at Harwell, Harwell Science & Innovation Campus, Didcot, UK.
  • Brewitz L; Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, Chemistry Research Laboratory, University of Oxford, Oxford, UK.
  • McDonough MA; Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, Chemistry Research Laboratory, University of Oxford, Oxford, UK.
  • Salah E; Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, Chemistry Research Laboratory, University of Oxford, Oxford, UK.
  • Terasaka N; Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, Chemistry Research Laboratory, University of Oxford, Oxford, UK.
  • Katoh T; Department of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
  • Lukacik P; Department of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
  • Strain-Damerell C; Diamond Light Source, Harwell Science & Innovation Campus, Didcot, UK.
  • Mikolajek H; Research Complex at Harwell, Harwell Science & Innovation Campus, Didcot, UK.
  • Walsh MA; Diamond Light Source, Harwell Science & Innovation Campus, Didcot, UK.
  • Kawamura A; Research Complex at Harwell, Harwell Science & Innovation Campus, Didcot, UK.
  • Schofield CJ; Diamond Light Source, Harwell Science & Innovation Campus, Didcot, UK.
  • Suga H; Research Complex at Harwell, Harwell Science & Innovation Campus, Didcot, UK.
Nat Chem ; 15(7): 998-1005, 2023 07.
Article en En | MEDLINE | ID: mdl-37217786

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: COVID-19 / Aminoácidos Idioma: En Revista: Nat Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Japón

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: COVID-19 / Aminoácidos Idioma: En Revista: Nat Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Japón