Clonal evolution in tyrosine kinase inhibitor-resistance: lessons from <i>in vitro</i>-models.

Kaehler, Meike; Osteresch, Pia; Künstner, Axel; Vieth, Stella Juliane; Esser, Daniela; Möller, Marius; Busch, Hauke; Vater, Inga; Spielmann, Malte; Cascorbi, Ingolf; Nagel, Inga

Clonal evolution in tyrosine kinase inhibitor-resistance: lessons from in vitro-models.

Kaehler, Meike; Osteresch, Pia; Künstner, Axel; Vieth, Stella Juliane; Esser, Daniela; Möller, Marius; Busch, Hauke; Vater, Inga; Spielmann, Malte; Cascorbi, Ingolf; Nagel, Inga.

Afiliación

Kaehler M; Institute of Experimental and Clinical Pharmacology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Osteresch P; Institute of Experimental and Clinical Pharmacology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Künstner A; Medical Systems Biology Group, University of Lübeck, Lübeck, Germany.
Vieth SJ; Institute of Cardiogenetics, University of Lübeck, Lübeck, Germany.
Esser D; Institute of Experimental and Clinical Pharmacology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Möller M; Institute of Clinical Chemistry, University Hospital Schleswig-Holstein, Kiel, Germany.
Busch H; Medical Systems Biology Group, University of Lübeck, Lübeck, Germany.
Vater I; Institute of Cardiogenetics, University of Lübeck, Lübeck, Germany.
Spielmann M; Medical Systems Biology Group, University of Lübeck, Lübeck, Germany.
Cascorbi I; Institute of Cardiogenetics, University of Lübeck, Lübeck, Germany.
Nagel I; Institute of Human Genetics, University Hospital Schleswig-Holstein, Kiel, Germany.

Front Oncol ; 13: 1200897, 2023.

Article en En | MEDLINE | ID: mdl-37384296

Palabras clave

KRAS; NRAS; PDGFRB; PTPN11; chronic myeloid leukemia; drug resistance; imatinib; nilotinib

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Front Oncol Año: 2023 Tipo del documento: Article País de afiliación: Alemania