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Advanced imaging techniques for tracking drug dynamics at the subcellular level.
Zhang, Chengying; Tian, Zhiqi; Chen, Rui; Rowan, Fiona; Qiu, Kangqiang; Sun, Yujie; Guan, Jun-Lin; Diao, Jiajie.
Afiliación
  • Zhang C; Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
  • Tian Z; Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
  • Chen R; Department of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA.
  • Rowan F; Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
  • Qiu K; Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
  • Sun Y; Department of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA.
  • Guan JL; Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
  • Diao J; Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA. Electronic address: jiajie.diao@uc.edu.
Adv Drug Deliv Rev ; 199: 114978, 2023 Aug.
Article en En | MEDLINE | ID: mdl-37385544
Optical microscopes are an important imaging tool that have effectively advanced the development of modern biomedicine. In recent years, super-resolution microscopy (SRM) has become one of the most popular techniques in the life sciences, especially in the field of living cell imaging. SRM has been used to solve many problems in basic biological research and has great potential in clinical application. In particular, the use of SRM to study drug delivery and kinetics at the subcellular level enables researchers to better study drugs' mechanisms of action and to assess the efficacy of their targets in vivo. The purpose of this paper is to review the recent advances in SRM and to highlight some of its applications in assessing subcellular drug dynamics.
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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Adv Drug Deliv Rev Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Adv Drug Deliv Rev Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos