Prognostic Value of Inflammatory Bowel Disease-associated Biomarkers in Patients With Immune Checkpoint Inhibitor Enterocolitis: A Retrospective Cohort Study.

Kogan, Lawrence; Townsend, Matthew J; Raj, Dhanya; Levy, Alexander N; Giobbie-Hurder, Anita; Grover, Shilpa

Kogan, Lawrence; Townsend, Matthew J; Raj, Dhanya; Levy, Alexander N; Giobbie-Hurder, Anita; Grover, Shilpa.

Afiliación

Kogan L; Division of Digestive Diseases, Yale School of Medicine, New Haven, CT, USA.
Townsend MJ; Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Raj D; Division of Gastroenterology, Hepatology, and Endoscopy, Brigham & Women's Hospital, Boston, MA, USA.
Levy AN; Division of Gastroenterology, Tufts Medical Center, Boston, MA, USA.
Giobbie-Hurder A; Division of Biostatistics, Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, USA.
Grover S; Division of Gastroenterology, Hepatology, and Endoscopy, Brigham & Women's Hospital, Boston, MA, USA.

Inflamm Bowel Dis ; 2023 Jul 08.

Article en En | MEDLINE | ID: mdl-37421640

In the emerging field of immune checkpoint inhibitor enterocolitis, biomarkers to predict disease course are lacking. Select genetic polymorphisms (ATG16L1T300A) and serum amyloid A warrant further study as potential biomarkers associated with severe ICI enterocolitis.

Palabras clave

biologic; biomarker; colitis; immune checkpoint inhibitor; immune-related adverse event

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Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Inflamm Bowel Dis Asunto de la revista: GASTROENTEROLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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