150 risk variants for diverticular disease of intestine prioritize cell types and enable polygenic prediction of disease susceptibility.

Wu, Yeda; Goleva, Slavina B; Breidenbach, Lindsay B; Kim, Minsoo; MacGregor, Stuart; Gandal, Michael J; Davis, Lea K; Wray, Naomi R

Wu, Yeda; Goleva, Slavina B; Breidenbach, Lindsay B; Kim, Minsoo; MacGregor, Stuart; Gandal, Michael J; Davis, Lea K; Wray, Naomi R.

Afiliación

Wu Y; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Goleva SB; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4029, Australia.
Breidenbach LB; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Kim M; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
MacGregor S; Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Gandal MJ; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Davis LK; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Wray NR; Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

Cell Genom ; 3(7): 100326, 2023 Jul 12.

Article en En | MEDLINE | ID: mdl-37492107

Palabras clave

GWAS; biobank; cross-ancestry polygenic prediction; diverticular disease; enteric nervous system; gut motility; polygenic score; scRNA seq

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Cell Genom Año: 2023 Tipo del documento: Article País de afiliación: Australia

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google