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Discovery of triazole-bridged aryl adamantane analogs as an intriguing class of multifunctional agents for treatment of Alzheimer's disease.
Gutti, Gopichand; Leifeld, Jennifer; Kakarla, Ramakrishna; Bajad, Nilesh Gajanan; Ganeshpurkar, Ankit; Kumar, Ashok; Krishnamurthy, Sairam; Klein-Schmidt, Christina; Tapken, Daniel; Hollmann, Michael; Singh, Sushil Kumar.
Afiliación
  • Gutti G; Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi, 221005, India; Department of Biochemistry I - Receptor Biochemistry, Faculty of Chemistry and Biochemistry, Ruhr University Bochum, Bochum, Germany.
  • Leifeld J; Department of Biochemistry I - Receptor Biochemistry, Faculty of Chemistry and Biochemistry, Ruhr University Bochum, Bochum, Germany.
  • Kakarla R; Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi, 221005, India.
  • Bajad NG; Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi, 221005, India.
  • Ganeshpurkar A; Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi, 221005, India.
  • Kumar A; Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi, 221005, India.
  • Krishnamurthy S; Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi, 221005, India.
  • Klein-Schmidt C; Department of Biochemistry I - Receptor Biochemistry, Faculty of Chemistry and Biochemistry, Ruhr University Bochum, Bochum, Germany.
  • Tapken D; Department of Biochemistry I - Receptor Biochemistry, Faculty of Chemistry and Biochemistry, Ruhr University Bochum, Bochum, Germany.
  • Hollmann M; Department of Biochemistry I - Receptor Biochemistry, Faculty of Chemistry and Biochemistry, Ruhr University Bochum, Bochum, Germany.
  • Singh SK; Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi, 221005, India. Electronic address: sksingh.phe@iitbhu.ac.in.
Eur J Med Chem ; 259: 115670, 2023 Nov 05.
Article en En | MEDLINE | ID: mdl-37515920
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Triazoles / Fármacos Neuroprotectores / Enfermedad de Alzheimer / Neuroblastoma Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Eur J Med Chem Año: 2023 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Triazoles / Fármacos Neuroprotectores / Enfermedad de Alzheimer / Neuroblastoma Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Eur J Med Chem Año: 2023 Tipo del documento: Article País de afiliación: Alemania