Decidual macrophages derived NO downregulates PD-L1 in trophoblasts leading to decreased Treg cells in recurrent miscarriage.

Zhang, Yonghong; Wang, Huiyan; Qiu, Panpan; Jiang, Jingwen; Wu, Xuhong; Mei, Jie; Sun, Haixiang

Zhang, Yonghong; Wang, Huiyan; Qiu, Panpan; Jiang, Jingwen; Wu, Xuhong; Mei, Jie; Sun, Haixiang.

Afiliación

Zhang Y; Center for Reproductive Medicine and Obstetrics and Gynecology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Wang H; Center for Reproductive Medicine and Obstetrics and Gynecology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Qiu P; Center for Reproductive Medicine and Obstetrics and Gynecology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Jiang J; Center for Reproductive Medicine and Obstetrics and Gynecology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Wu X; Center for Reproductive Medicine and Obstetrics and Gynecology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Mei J; Center for Reproductive Medicine and Obstetrics and Gynecology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Sun H; Center for Reproductive Medicine and Obstetrics and Gynecology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.

Front Immunol ; 14: 1180154, 2023.

Article en En | MEDLINE | ID: mdl-37520550

Asunto(s)

Aborto Habitual; Trofoblastos; Animales; Femenino; Humanos; Ratones; Embarazo; Aborto Habitual/metabolismo; Antígeno B7-H1/genética; Antígeno B7-H1/metabolismo; Macrófagos/metabolismo; Placenta/metabolismo; Receptor de Muerte Celular Programada 1/metabolismo; Linfocitos T Reguladores/metabolismo; Trofoblastos/metabolismo

Palabras clave

NO; PD-L1; Treg; YY1; decidual macrophage; recurrent miscarriage; trophoblast

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Trofoblastos / Aborto Habitual Límite: Animals / Female / Humans / Pregnancy Idioma: En Revista: Front Immunol Año: 2023 Tipo del documento: Article País de afiliación: China

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