Integrative analysis reveals that SLC38A1 promotes hepatocellular carcinoma development via PI3K/AKT/mTOR signaling via glutamine mediated energy metabolism.

Feng, Hua-Guo; Wu, Chuan-Xin; Zhong, Guo-Chao; Gong, Jian-Ping; Miao, Chun-Mu; Xiong, Bin

Feng, Hua-Guo; Wu, Chuan-Xin; Zhong, Guo-Chao; Gong, Jian-Ping; Miao, Chun-Mu; Xiong, Bin.

Afiliación

Feng HG; Department of Hepatobiliary Surgery, the Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, No. 74 Linjiang Road, Chongqing, China.
Wu CX; Department of Hepatobiliary Surgery, the Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, No. 74 Linjiang Road, Chongqing, China.
Zhong GC; Department of Hepatobiliary Surgery, the Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, No. 74 Linjiang Road, Chongqing, China.
Gong JP; Department of Hepatobiliary Surgery, the Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, No. 74 Linjiang Road, Chongqing, China.
Miao CM; Department of Hepatobiliary Surgery, the Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, No. 74 Linjiang Road, Chongqing, China.
Xiong B; Department of Hepatobiliary Surgery, the Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, No. 74 Linjiang Road, Chongqing, China. 304370@hospital.cqmu.edu.cn.

J Cancer Res Clin Oncol ; 149(17): 15879-15898, 2023 Nov.

Article en En | MEDLINE | ID: mdl-37673823

Asunto(s)

Carcinoma Hepatocelular; Neoplasias Hepáticas; Humanos; Carcinoma Hepatocelular/patología; Proteínas Proto-Oncogénicas c-akt/metabolismo; Fosfatidilinositol 3-Quinasas/genética; Fosfatidilinositol 3-Quinasas/metabolismo; Glutamina/metabolismo; Neoplasias Hepáticas/patología; Proliferación Celular/genética; Serina-Treonina Quinasas TOR/genética; Serina-Treonina Quinasas TOR/metabolismo; Metabolismo Energético; Línea Celular Tumoral; Sistema de Transporte de Aminoácidos A/metabolismo

Palabras clave

Biomarker; Glutamine; Hepatocellular carcinoma; Metabolismrelated genes; PI3K/AKT/mTOR signaling; SLC38A1

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Cancer Res Clin Oncol Año: 2023 Tipo del documento: Article País de afiliación: China

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google