Acetylation encodes Tau aggregation.
Structure
; 31(9): 1005-1007, 2023 09 07.
Article
en En
| MEDLINE
| ID: mdl-37683614
ABSTRACT
Post-translational modifications profoundly influence amyloid assembly. In this issue of Structure, Li et al. unravel the underlying mechanism by which specific lysine acetylation patterns facilitate fibril formation of Tau segments. Their cryo-electron microscopy structure further elucidates how acetyl groups act as stabilizers within the architecture of Tau fibrils.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Citoesqueleto
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Lisina
Idioma:
En
Revista:
Structure
Asunto de la revista:
BIOLOGIA MOLECULAR
/
BIOQUIMICA
/
BIOTECNOLOGIA
Año:
2023
Tipo del documento:
Article
País de afiliación:
China