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Targeted activation of human ether-à-go-go-related gene channels rescues electrical instability induced by the R56Q+/- long QT syndrome variant.
Venkateshappa, Ravichandra; Hunter, Diana V; Muralidharan, Priya; Nagalingam, Raghu S; Huen, Galvin; Faizi, Shoaib; Luthra, Shreya; Lin, Eric; Cheng, Yen May; Hughes, Julia; Khelifi, Rania; Dhunna, Daman Parduman; Johal, Raj; Sergeev, Valentine; Shafaattalab, Sanam; Julian, Lisa M; Poburko, Damon T; Laksman, Zachary; Tibbits, Glen F; Claydon, Tom W.
Afiliación
  • Venkateshappa R; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.
  • Hunter DV; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.
  • Muralidharan P; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.
  • Nagalingam RS; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.
  • Huen G; Cellular and Regenerative Medicine Centre, British Columbia Children's Hospital Research Institute, 938 W 28th Ave, Vancouver, BC, Canada V5Z 4H4.
  • Faizi S; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.
  • Luthra S; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.
  • Lin E; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.
  • Cheng YM; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.
  • Hughes J; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.
  • Khelifi R; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.
  • Dhunna DP; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.
  • Johal R; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.
  • Sergeev V; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.
  • Shafaattalab S; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.
  • Julian LM; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.
  • Poburko DT; Department of Biological Sciences, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.
  • Laksman Z; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.
  • Tibbits GF; Department of Medicine, School of Biomedical Engineering, University of British Columbia, 2194 Health Sciences Mall, Vancouver, BC, Canada V6T 1Z3.
  • Claydon TW; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada V5A 1S6.
Cardiovasc Res ; 119(15): 2522-2535, 2023 11 25.
Article en En | MEDLINE | ID: mdl-37739930
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Síndrome de QT Prolongado / Canales de Potasio Éter-A-Go-Go Límite: Humans Idioma: En Revista: Cardiovasc Res Año: 2023 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Síndrome de QT Prolongado / Canales de Potasio Éter-A-Go-Go Límite: Humans Idioma: En Revista: Cardiovasc Res Año: 2023 Tipo del documento: Article