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First-in-class metallo-PROTAC as an effective degrader of select Pt-binding proteins.
O'Dowd, Paul D; Sullivan, Graeme P; Rodrigues, Daniel A; Chonghaile, Tríona Ní; Griffith, Darren M.
Afiliación
  • O'Dowd PD; Department of Chemistry, Royal College of Surgeons in Ireland, Dublin 2, Ireland. dgriffith@rcsi.ie.
  • Sullivan GP; SSPC, the Science Foundation Ireland Research Centre for Pharmaceuticals, Ireland.
  • Rodrigues DA; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • Chonghaile TN; Department of Chemistry, Royal College of Surgeons in Ireland, Dublin 2, Ireland. dgriffith@rcsi.ie.
  • Griffith DM; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Chem Commun (Camb) ; 59(84): 12641-12644, 2023 Oct 19.
Article en En | MEDLINE | ID: mdl-37791917

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Portadoras / Neoplasias Límite: Humans Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Irlanda

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Portadoras / Neoplasias Límite: Humans Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Irlanda