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Applied physiologically-based pharmacokinetic modeling to assess uridine diphosphate-glucuronosyltransferase-mediated drug-drug interactions for Vericiguat.
Frechen, Sebastian; Ince, Ibrahim; Dallmann, André; Gerisch, Michael; Jungmann, Natalia A; Becker, Corina; Lobmeyer, Maximilian; Trujillo, Maria E; Xu, Shiyao; Burghaus, Rolf; Meyer, Michaela.
Afiliación
  • Frechen S; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
  • Ince I; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
  • Dallmann A; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
  • Gerisch M; DMPK, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
  • Jungmann NA; DMPK, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
  • Becker C; Clinical Pharmacology, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
  • Lobmeyer M; Clinical Pharmacology, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
  • Trujillo ME; Merck & Co., Inc., Rahway, New Jersey, USA.
  • Xu S; Merck & Co., Inc., Rahway, New Jersey, USA.
  • Burghaus R; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
  • Meyer M; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
CPT Pharmacometrics Syst Pharmacol ; 13(1): 79-92, 2024 Jan.
Article en En | MEDLINE | ID: mdl-37794724
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirimidinas / Ácido Mefenámico / Glucuronosiltransferasa / Compuestos Heterocíclicos con 2 Anillos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: CPT Pharmacometrics Syst Pharmacol Año: 2024 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirimidinas / Ácido Mefenámico / Glucuronosiltransferasa / Compuestos Heterocíclicos con 2 Anillos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: CPT Pharmacometrics Syst Pharmacol Año: 2024 Tipo del documento: Article País de afiliación: Alemania