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The FLT3N701K mutation causes clinical AML resistance to gilteritinib and triggers TKI sensitivity switch to quizartinib.
Joshi, Sunil K; Pittsenbarger, Janét; Kennedy, Vanessa E; Peretz, Cheryl A C; Perl, Alexander E; Smith, Catherine C; Tyner, Jeffrey W; Druker, Brian J; Traer, Elie.
Afiliación
  • Joshi SK; Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.
  • Pittsenbarger J; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.
  • Kennedy VE; Division of Hematology & Medical Oncology, Department of Medicine, Oregon Health & Science University, Portland, Oregon, USA.
  • Peretz CAC; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.
  • Perl AE; Division of Hematology and Oncology, Department of Medicine, University of California San Francisco, San Francisco, California, USA.
  • Smith CC; Division of Hematology and Oncology, Department of Pediatrics, University of California San Francisco, San Francisco, California, USA.
  • Tyner JW; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USA.
  • Druker BJ; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Traer E; Division of Hematology and Oncology, Department of Medicine, University of California San Francisco, San Francisco, California, USA.
Am J Hematol ; 98(12): E364-E368, 2023 12.
Article en En | MEDLINE | ID: mdl-37815132
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Antineoplásicos Tipo de estudio: Diagnostic_studies / Etiology_studies Límite: Humans Idioma: En Revista: Am J Hematol Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Antineoplásicos Tipo de estudio: Diagnostic_studies / Etiology_studies Límite: Humans Idioma: En Revista: Am J Hematol Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos