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[Endoscopic treatment of obstructive jaundice in patients with Klatskin tumor]. / Endoskopicheskoe lechenie patsientov s mekhanicheskoi zheltukhoi pri opukholi Klatskina.
Kachmazova, A V; Teterin, Yu S; Tigiev, L R; Yartsev, P A; Rogal, M L; Bayramov, R Sh.
Afiliación
  • Kachmazova AV; Sklifosovsky Research Institute for Emergency Care, Moscow, Russia.
  • Teterin YS; Sklifosovsky Research Institute for Emergency Care, Moscow, Russia.
  • Tigiev LR; Sklifosovsky Research Institute for Emergency Care, Moscow, Russia.
  • Yartsev PA; Sklifosovsky Research Institute for Emergency Care, Moscow, Russia.
  • Rogal ML; Sklifosovsky Research Institute for Emergency Care, Moscow, Russia.
  • Bayramov RS; Sklifosovsky Research Institute for Emergency Care, Moscow, Russia.
Khirurgiia (Mosk) ; (4): 55-60, 2023.
Article en Ru | MEDLINE | ID: mdl-37850895
OBJECTIVE: To improve treatment outcomes in patients with Klatskin tumor and obstructive jaundice by using of endoscopic bilioduodenal stenting. MATERIAL AND METHODS: There were 1904 transpapillary interventions between August 2017 and February 2022. Endoscopic bilioduodenal stenting was performed in 250 patients including 25 (10%) ones with Klatskin tumor. RESULTS: Bilioduodenal plastic and self-expanding stents were installed in 19 (76%) and 6 (24%) patients, respectively. In Klatskin tumor type I, 11 patients (44%) underwent bilioduodenal stenting of common hepatic duct with plastic stent; 5 (20%) patients with Klatskin tumor type II received self-expanding stents. In case of tumor type IIIA, 3 (12%) patients underwent stenting of the right lobar duct with plastic stent. Four (16%) patients with Klatskin tumor type III B underwent stenting of the left lobar duct. Two 2 (8%) patients with Klatskin tumor type IV underwent bilateral bilioduodenal stenting with plastic and bifurcation self-expanding stents. Peroral cholangioscopy using the SpyGlass DS system was performed in 4 (16%) patients. No intraoperative complications were identified. One (4%) patient developed gastrointestinal bleeding in 2 postoperative days after retrograde intervention that did not require surgery. Moreover, 1 (4%) patient with distal dislocation of plastic bilioduodenal stent required redo bilioduodenal stenting. Three (12%) patients died from multiple organ failure despite adequate biliary decompression, and 22 (88%) patients were discharged in 8±5 days after retrograde intervention. CONCLUSION: Bilioduodenal stenting as minimally invasive and physiological method was highly effective for obstructive jaundice in patients with Klatskin tumor. Peroral cholangioscopy using the SpyGlass system provides effective and safe direct visualization of the biliary tract, as well as biopsy for morphological verification and prescription of chemotherapy in patients with intraductal growth of tumor.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias de los Conductos Biliares / Colestasis / Tumor de Klatskin / Ictericia Obstructiva Límite: Humans Idioma: Ru Revista: Khirurgiia (Mosk) Año: 2023 Tipo del documento: Article País de afiliación: Rusia

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias de los Conductos Biliares / Colestasis / Tumor de Klatskin / Ictericia Obstructiva Límite: Humans Idioma: Ru Revista: Khirurgiia (Mosk) Año: 2023 Tipo del documento: Article País de afiliación: Rusia