A cluster randomised controlled trial to reduce respiratory effects of cotton dust exposure among textile workers: the MultiTex RCT study.
Eur Respir J
; 63(1)2024 Jan.
Article
en En
| MEDLINE
| ID: mdl-37857425
ABSTRACT
BACKGROUND:
We determined the effectiveness of an intervention to reduce cotton dust-related respiratory symptoms and improve lung function of textile workers.METHODS:
We undertook a cluster randomised controlled trial at 38 textile mills in Karachi, Pakistan. The intervention comprised training in occupational health for workers and managers, formation of workplace committees to promote a health and safety plan that included wet mopping and safe disposal of cotton dust, provision of simple face masks, and further publicity about the risks from cotton dust. Participating mills were randomised following baseline data collection. The impact of the intervention was measured through surveys at 3, 12 and 18â months using questionnaires, spirometry and dust measurements. The primary outcomes were 1) changes in prevalence of a composite respiratory symptom variable, 2) changes in post-bronchodilator percentage predicted forced expiratory volume in 1â s (FEV1) and 3) changes in cotton dust levels. These were assessed using two-level mixed effects linear and logistic regression.RESULTS:
Of 2031 participants recruited at baseline, 807 (40%) were available at the third follow-up. At that point, workers in the intervention arm were more likely to report an improvement in respiratory symptoms (OR 1.58, 95% CI 1.06-2.36) and lung function (FEV1 % pred ß 1.31%, 95% CI 0.04-2.57%). Personal dust levels decreased, more so in intervention mills, although we did not observe this in adjusted models due to the small number of samples.CONCLUSION:
We found the intervention to be effective in improving the respiratory health of textile workers and recommend scaling-up of such simple and feasible interventions in low- and middle-income countries.
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Bases de datos:
MEDLINE
Asunto principal:
Exposición Profesional
/
Enfermedades Pulmonares
Límite:
Humans
Idioma:
En
Revista:
Eur Respir J
Año:
2024
Tipo del documento:
Article
País de afiliación:
Pakistán