A Bioorthogonal Decaging Chemistry of N-Oxide and Silylborane for Prodrug Activation both In Vitro and In Vivo.

Yan, Zhicheng; Pan, Yiyao; Jiao, Guofeng; Xu, Mengyu; Fan, Dongguang; Hu, Ziwei; Wu, Jiarui; Chen, Tao; Liu, Miao; Bao, Xiaoguang; Ke, Hengte; Ji, Xingyue

A Bioorthogonal Decaging Chemistry of N-Oxide and Silylborane for Prodrug Activation both In Vitro and In Vivo.

Yan, Zhicheng; Pan, Yiyao; Jiao, Guofeng; Xu, Mengyu; Fan, Dongguang; Hu, Ziwei; Wu, Jiarui; Chen, Tao; Liu, Miao; Bao, Xiaoguang; Ke, Hengte; Ji, Xingyue.

Afiliación

Yan Z; College of Pharmaceutical Science, Soochow University, Suzhou, Jiangsu 215021, China.
Pan Y; College of Pharmaceutical Science, Soochow University, Suzhou, Jiangsu 215021, China.
Jiao G; College of Pharmaceutical Science, Soochow University, Suzhou, Jiangsu 215021, China.
Xu M; College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, Jiangsu 215123, China.
Fan D; College of Pharmaceutical Science, Soochow University, Suzhou, Jiangsu 215021, China.
Hu Z; College of Pharmaceutical Science, Soochow University, Suzhou, Jiangsu 215021, China.
Wu J; College of Pharmaceutical Science, Soochow University, Suzhou, Jiangsu 215021, China.
Chen T; College of Pharmaceutical Science, Soochow University, Suzhou, Jiangsu 215021, China.
Liu M; College of Pharmaceutical Science, Soochow University, Suzhou, Jiangsu 215021, China.
Bao X; College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, Jiangsu 215123, China.
Ke H; College of Pharmaceutical Science, Soochow University, Suzhou, Jiangsu 215021, China.
Ji X; College of Pharmaceutical Science, Soochow University, Suzhou, Jiangsu 215021, China.

J Am Chem Soc ; 2023 Nov 07.

Article en En | MEDLINE | ID: mdl-37933858

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: J Am Chem Soc Año: 2023 Tipo del documento: Article País de afiliación: China