Harnessing the effects of hypoxia-like inhibition on homology-directed DNA repair.

Altwerger, Gary; Ghazarian, Maddie; Glazer, Peter M

Altwerger, Gary; Ghazarian, Maddie; Glazer, Peter M.

Afiliación

Altwerger G; Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06511, USA.
Ghazarian M; Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06511, USA.
Glazer PM; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06511, USA; Department of Genetics, Yale University School of Medicine, New Haven, CT 06511, USA. Electronic address: peter.glazer@yale.edu.

Semin Cancer Biol ; 98: 11-18, 2024 Jan.

Article en En | MEDLINE | ID: mdl-38029867

Asunto(s)

Antineoplásicos; Neoplasias; Humanos; Inhibidores de Poli(ADP-Ribosa) Polimerasas/farmacología; Inhibidores de Poli(ADP-Ribosa) Polimerasas/uso terapéutico; Poli(ADP-Ribosa) Polimerasas/metabolismo; Poli(ADP-Ribosa) Polimerasas/farmacología; Reparación del ADN; Antineoplásicos/farmacología; Neoplasias/tratamiento farmacológico; Neoplasias/genética; Hipoxia/genética; Microambiente Tumoral

Palabras clave

BRCA; Cediranib; DNA repair; Homologous recombination; Hypoxia; Immune checkpoint inhibitors; Immune therapy; RAD51; Synthetic lethality

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias / Antineoplásicos Límite: Humans Idioma: En Revista: Semin Cancer Biol Asunto de la revista: NEOPLASIAS Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google