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An epithelial gene signature of trans-IL-6 signaling defines a subgroup of type 2-low asthma.
El-Husseini, Zaid W; Khalenkow, Dmitry; Lan, Andy; van der Molen, Thys; Brightling, Chris; Papi, Alberto; Rabe, Klaus F; Siddiqui, Salman; Singh, Dave; Kraft, Monica; Beghe, Bianca; van den Berge, Maarten; van Gosliga, Djoke; Nawijn, Martijn C; Rose-John, Stefan; Koppelman, Gerard H; Gosens, Reinoud.
Afiliación
  • El-Husseini ZW; Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
  • Khalenkow D; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.
  • Lan A; Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, University of Groningen, 9713 AV, Groningen, The Netherlands.
  • van der Molen T; Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
  • Brightling C; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.
  • Papi A; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.
  • Rabe KF; Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, University of Groningen, 9713 AV, Groningen, The Netherlands.
  • Siddiqui S; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.
  • Singh D; Department of Infection, Immunity and Inflammation, Institute for Lung Health, University of Leicester, Leicester, UK.
  • Kraft M; Department of Respiratory Medicine, University of Ferrara, Ferrara, Italy.
  • Beghe B; Department of Medicine, Christian Albrechts University Kiel, Kiel and Lungen Clinic Grosshansdorf (Members of the German Center for Lung Research (DZL)), Grosshansdorf, Germany.
  • van den Berge M; National Heart and Lung Institute, Imperial College and Imperial NIHR Biomedical Research Centre, London, UK.
  • van Gosliga D; Medicines Evaluation Unit, Manchester University NHS Foundation Hospital Trust, University of Manchester, Manchester, UK.
  • Nawijn MC; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.
  • Rose-John S; University of Modena and Reggio Emilia, AOU of Modena, Modena, Italy.
  • Koppelman GH; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.
  • Gosens R; Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Respir Res ; 24(1): 308, 2023 Dec 07.
Article en En | MEDLINE | ID: mdl-38062491

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Asma / Interleucina-6 Límite: Humans Idioma: En Revista: Respir Res Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Asma / Interleucina-6 Límite: Humans Idioma: En Revista: Respir Res Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos