Gene-edited protein kinases and phosphatases in molecular plant breeding.
Trends Plant Sci
; 29(6): 694-710, 2024 Jun.
Article
en En
| MEDLINE
| ID: mdl-38151445
ABSTRACT
Protein phosphorylation, the most common and essential post-translational modification, belongs to crucial regulatory mechanisms in plants, affecting their metabolism, intracellular transport, cytoarchitecture, cell division, growth, development, and interactions with the environment. Protein kinases and phosphatases, two important families of enzymes optimally regulating phosphorylation, have now become important targets for gene editing in crops. We review progress on gene-edited protein kinases and phosphatases in crops using clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9). We also provide guidance for computational prediction of alterations and/or changes in function, activity, and binding of protein kinases and phosphatases as consequences of CRISPR/Cas9-based gene editing with its possible application in modern crop molecular breeding towards sustainable agriculture.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Proteínas Quinasas
/
Productos Agrícolas
/
Sistemas CRISPR-Cas
/
Fitomejoramiento
/
Edición Génica
Idioma:
En
Revista:
Trends Plant Sci
Asunto de la revista:
BOTANICA
Año:
2024
Tipo del documento:
Article
País de afiliación:
República Checa