Nerve enlargement differs among chronic inflammatory demyelinating polyradiculoneuropathy subtypes and multifocal motor neuropathy.
Clin Neurophysiol Pract
; 8: 228-234, 2023.
Article
en En
| MEDLINE
| ID: mdl-38152246
ABSTRACT
Objective:
We aimed to evaluate differences in ultrasonographic nerve enlargement sites among typical chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), distal CIDP, multifocal CIDP and multifocal motor neuropathy (MMN) in a Japanese population.Methods:
We retrospectively reviewed medical records and selected 39 patients (14 with typical CIDP, 7 with multifocal CIDP, 4 with distal CIDP, and 14 with MMN) who underwent ultrasonography. Median and ulnar nerve cross-sectional areas (CSAs) were measured at the wrist, forearm, elbow, and upper arm. CSA ratios for each nerve were calculated as wrist-to-forearm index (WFI)â¯=â¯wrist CSA/forearm CSA; elbow-to-upper arm index (EUI)â¯=â¯elbow CSA/upper arm CSA; and intranerve CSA variability (INCV)â¯=â¯maximal CSA/minimal CSA.Results:
Significant differences were observed among typical CIDP, multifocal CIDP, distal CIDP, and MMN in CSA at the forearm and upper arm in the median nerves (pâ¯<â¯0.05). Patients with multifocal CIDP had lower WFI and EUI and higher INCV than the other groups (pâ¯<â¯0.05).Conclusions:
Regardless of the untreated period, compared with other CIDP subtypes and MMN, multifocal CIDP showed a focal and marked nerve enlargement in the Japanese population.Significance:
Differences in nerve enlargement site may be an underlying feature of multifocal CIDP.
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Bases de datos:
MEDLINE
Idioma:
En
Revista:
Clin Neurophysiol Pract
Año:
2023
Tipo del documento:
Article
País de afiliación:
Japón