Network pharmacology: towards the artificial intelligence-based precision traditional Chinese medicine.
Brief Bioinform
; 25(1)2023 11 22.
Article
en En
| MEDLINE
| ID: mdl-38197310
ABSTRACT
Network pharmacology (NP) provides a new methodological perspective for understanding traditional medicine from a holistic perspective, giving rise to frontiers such as traditional Chinese medicine network pharmacology (TCM-NP). With the development of artificial intelligence (AI) technology, it is key for NP to develop network-based AI methods to reveal the treatment mechanism of complex diseases from massive omics data. In this review, focusing on the TCM-NP, we summarize involved AI methods into three categories network relationship mining, network target positioning and network target navigating, and present the typical application of TCM-NP in uncovering biological basis and clinical value of Cold/Hot syndromes. Collectively, our review provides researchers with an innovative overview of the methodological progress of NP and its application in TCM from the AI perspective.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Inteligencia Artificial
/
Medicina Tradicional China
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
En
Revista:
Brief Bioinform
Asunto de la revista:
BIOLOGIA
/
INFORMATICA MEDICA
Año:
2023
Tipo del documento:
Article
País de afiliación:
China