Relationship between bullous pemphigoid and malignancy: A Mendelian randomization study.
J Dermatol
; 51(3): 403-408, 2024 Mar.
Article
en En
| MEDLINE
| ID: mdl-38212903
ABSTRACT
Bullous pemphigoid (BP) is the most common autoimmune blistering disease, which primarily affects the elderly. However, the relationship between BP and malignancy remains controversial in traditional observational studies. The aim of this study, which included only European populations, was to assess the potential causative link between BP and 13 types of malignant tumors in a two-sample Mendelian randomization (MR) study. BP was not associated with an increased risk of developing 13 types of malignant tumors. This study did not find a causal relationship between BP and malignant tumors. However, further research is warranted to examine the generalizability of this conclusion in non-European populations.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Enfermedades Autoinmunes
/
Penfigoide Ampolloso
/
Neoplasias
Tipo de estudio:
Clinical_trials
/
Observational_studies
Límite:
Aged
/
Humans
Idioma:
En
Revista:
J Dermatol
Año:
2024
Tipo del documento:
Article
País de afiliación:
China